This cross-border region includes the cities of Austin, San Antonio, Corpus Christi, Laredo, McAllen, Harlingen, Brownsville, Matamoros, Reynosa, Nuevo Laredo, Saltillo and Monterrey. The combined population in this region exceeds 10 million people.

This area is a state-of-the-industry multimodal logistics and transportation hub. The new USMCA trade pact that was executed on July 1, 2020 supports an established multimodal logistics corridor between the USA and Mexico and creates momentum for Closeshoring™. The Port of Brownsville is the closest US port to Mexico. This region is served by two additional major US ports: The Port of Corpus Christi and Port Houston and in Mexico, by the Port of Altamira. Five national Class I railroads serve this region: Union Pacific, BNSF, Kansas City Southern, Kansas City Southern de Mexico, and Ferromex. This area has a 377 kilometer border with South Texas and every day 40% of the commerce between Mexico and the USA flows through this region, including 17,000 trucks per day. (Source: Tamaulipas Economic Development Agency September 26, 2020). Most major trucking and logistics companies and many medium and small transportation companies also provide service to this region. International and domestic air cargo services are also available from multiple airports. 

This region boasts a skilled workforce, attractive communities, excellent educational systems and universities, and an affordable cost of living. South Texas and Northeastern Mexico is home to major industrial companies involved in automotive, aerospace, electronics, high technology, energy, transportation, medical products, pharmaceuticals, agriculture, steel and other metals, among many more. This area is a robust international industrial and commercial hub that benefits from extensive cultural and economic ties between the two countries.